In an interview with Oprah Winfrey that is scheduled for broadcast on her network on Thursday, Lance Armstrong confessed that he used performance-enhancing drugs during his cycling career, according to two people briefed on the interview, which was recorded Monday in Austin, Tex.

It is unclear, though, how forthcoming Armstrong was about his doping program, which the United States Anti-Doping Agency has said was part of the most sophisticated, organized and professional doping scheme in the history of sports. Armstrong, when reached by e-mail Monday, said he could not discuss the interview.

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